Cyclopeptides Natural Products as Herbicides and Inhibitors of Cyanobacteria: Synthesis of Versicotides E and F

The first total syntheses of cyclopeptides versicotide E and F, containing anthranilic acid, are reported. Evaluation the herbicide activity, cyanobacteria inhibition microcystins concentration all versicotides A?F demonstrated that several them could be considered as lead candidates in development bioherbicides to mitigate environmental impact evolution agriculture has had on water quality.